Exhibit 21

2

Bio-Techne Corporation, a Minnesota corporation, had the material subsidiaries below as of the date of filing its Annual Report on Form 10-K for fiscal year ended June 30, 2023. Certain subsidiaries are not named because they were not significant individually or in the aggregate as of such date. Bio-Techne Corporation is not a subsidiary of any other entity. 

Name

State/Country of Incorporation

Research and Diagnostic Systems Inc. (R&D Systems)

Minnesota

Bio-Techne China Co. Ltd

China

ProteinSimple

Delaware

ProteinSimple Ltd.

Canada

Novus Biologicals, LLC

Delaware

Bio-Techne Ltd.

United Kingdom

Advanced Cell Diagnostics, Inc.

California

Exosome Diagnostics, Inc. 

Delaware

Asuragen, Inc.

Delaware

Cyvek, Inc

Delaware