November 22, 2002 Securities and Exchange Commission Mail Stop 11-3 450 Fifth Street N.W. Washington, DC 20549 Dear Sirs/Madams: We have read and agree with the comments in the second, third and fourth paragraphs in Item 4 of TECHNE Corporation's Form 8-K dated November 18, 2002. We have no basis for agreeing or disagreeing with the comments in the first and fifth paragraphs. Yours truly, /s/ Deloitte & Touche LLP