FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Kummeth Charles R.
  2. Issuer Name and Ticker or Trading Symbol
BIO-TECHNE Corp [TECH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Executive Officer
(Last)
(First)
(Middle)
614 MCKINLEY PLACE NE
3. Date of Earliest Transaction (Month/Day/Year)
05/25/2021
(Street)

MINNEAPOLIS, MN 55413
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/25/2021   M   36,849 A $ 94.35 195,690 (1) D  
Common Stock 05/25/2021   F   21,305 D $ 420.12 174,385 (1) D  
Common Stock               100 I By Step-Son
Common Stock               100 I By Step-Daughter

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Options (Right to Buy) $ 94.35 05/25/2021   M     36,849   (2) 08/12/2021 Common Stock 36,849 $ 0 0 D  
Stock Options (Right to Buy) $ 108.49               (2) 08/07/2022 Common Stock 95,346   95,346 D  
Stock Options (Right to Buy) $ 108.49               (2) 08/07/2022 Common Stock 79,517   79,517 D  
Stock Options (Right to Buy) $ 106.59               (2) 08/18/2023 Common Stock 154,169   154,169 D  
Stock Options (Right to Buy) $ 106.59               (2) 08/18/2023 Common Stock 102,779   102,779 D  
Stock Options (Right to Buy) $ 125.05               (2) 08/09/2024 Common Stock 117,342   117,342 D  
Stock Options (Right to Buy) $ 125.05               (4) 08/09/2024 Common Stock 78,228   78,228 D  
Restricted Stock Units (3)               (5)   (5) Common Stock 16,918   16,918 D  
Stock Options (Right to Buy) $ 177.32               (5) 08/08/2025 Common Stock 90,334   90,334 D  
Stock Options (Right to Buy) $ 177.32               (6) 08/08/2025 Common Stock 60,222   60,222 D  
Restricted Stock Units (3)               (7)   (7) Common Stock 16,937   16,937 D  
Stock Options (Right to Buy) $ 190.41               (7) 08/07/2026 Common Stock 85,725   85,725 D  
Stock Options (Right to Buy) $ 190.41               (8) 08/07/2026 Common Stock 57,150   57,150 D  
Restricted Stock Units (3)               (9)   (9) Common Stock 12,879   12,879 D  
Stock Options (Right to Buy) $ 267.87               (9) 08/05/2027 Common Stock 57,442   57,442 D  
Stock Options (Right to Buy) $ 267.87               (10) 08/05/2027 Common Stock 38,295   38,295 D  
Stock Options (Right to Buy) $ 267.87               (11) 08/05/2027 Common Stock 16,650.00   16,650.00 D  
Stock Options (Right to Buy) $ 267.87               (12) 08/05/2027 Common Stock 16,650   16,650 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Kummeth Charles R.
614 MCKINLEY PLACE NE
MINNEAPOLIS, MN 55413
  X     Chief Executive Officer  

Signatures

 /s/ Brenda S. Furlow as Attorney-in-Fact for Charles R. Kummeth pursuant to Power of Attorney previously filed.   05/27/2021
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes (i) 3,759 shares of restricted stock for which the risk of forfeiture will lapse on August 8, 2021; (ii) 7,527 shares of restricted stock for which the risk of forfeiture will lapse with respect to 3,764 shares on August 7, 2021 and as to 3,763 shares on August 7, 2022; and (iii) 8,586 shares of restricted stock for which the risk of forfeiture will lapse as to 2,862 shares on each of August 5, 2021, August 5, 2022 and August 5, 2023.
(2) Fully exercisable.
(3) Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock.
(4) Options to purchase 19,557 shares vest on each of 8/9/2018, 8/9/2019, 8/9/2020 and 8/9/2021.
(5) Vests in full or in part on 8/8/2021 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(6) Options to purchase 15,056 shares vest on each of 8/8/2019 and 8/8/2020 and options to purchase 15,055 shares vest on each of 8/8/2021 and 8/8/2022.
(7) Vests in full or in part on 8/7/2022 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(8) Options to purchase 14,288 shares vest on each of 8/7/2020 and 8/7/2021 and options to purchase 14,287 shares vest on each of 8/7/2022 and 8/7/2023.
(9) Vests in full or in part on 8/5/2023 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(10) Options to purchase 9,573 shares vest on 8/5/21 and options to purchase 9,574 shares vest on each of 8/5/22, 8/5/23 and 8/5/24.