Registration No. 33-49156



                       SECURITIES AND EXCHANGE COMMISSION
                             Washington D.C. 20549


                         POST-EFFECTIVE AMENDMENT NO. 1

                                       TO
                                    FORM S-3
            REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933



                               TECHNE CORPORATION
                        (Name of issuer in its charter)



     Minnesota                                                41-1427402
(State or other juris-                                     (I.R.S. Employer
diction of incorporation                                 Identification Number)
or organization)



                               Techne Corporation
                            614 McKinley Place N.E.
                          Minneapolis, Minnesota 55413
                                 (612) 379-8854
        (Address and telephone number of principal executive offices and
                          principal place of business)




                                Thomas E. Oland
                                   President
                        Techne Corporation 
                            614 McKinley Place N.E.
                          Minneapolis, Minnesota 55413
                                 (612) 379-8854
           (Name, address and telephone number of agent for service)




                                   Copies to:

                            Timothy M. Heaney, Esq.
                            Fredrikson & Byron, P.A.
                      900 Second Avenue South, Suite 1100
                          Minneapolis, Minnesota 55402




                  Approximate date of commencement of proposed
                       sale to the public: Sales will not
                                   commence.





The Registrant hereby amends this  Registration  Statement on such date or dates
as may be necessary to delay its effective date until the Registrant  shall file
a further amendment which specifically  states that this Registration  Statement
shall  thereafter  become  effective  in  accordance  with  Section  8(a) of the
Securities  Act of  1933  or  until  the  Registration  Statement  shall  become
effective on such date as the Commission,  acting pursuant to said Section 8(a),
may determine.









         This  Post-Effective  Amendment is being filed to  de-register  537,066
shares of Common Stock (the "Shares") of Techne  Corporation (the  "Registrant")
which were registered under a Registration  Statement on Form S-3,  Registration
No.  33-49156  for  sale  by a  selling  shareholder.  As of the  date  of  this
Post-Effective Amendment, the Shares remain unsold and, since the holding period
under Rule 144(k) has been met with  respect to the Shares,  there is no further
need to maintain the Registration Statement in effect.

                                   SIGNATURES

         In accordance with the  requirements of the Securities Act of 1933, the
registrant certifies that it has reasonable grounds to believe that it meets all
of the  requirements for filing on Form S-3 and has caused this amendment to the
Registration  Statement  to be signed on its behalf by the  undersigned,  in the
City of Minneapolis, State of Minnesota, on October 19th, 1995.

                                       TECHNE CORPORATION


                                       By /s/ Thomas E. Oland
                                          Thomas E. Oland, President

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
amendment to the Registration Statement has been signed by the following persons
in the capacities and on the dates indicated.

Signature                Title                                Date


/s/ Thomas E. Oland      Chairman, President, Chief           October 19, 1995
Thomas E. Oland          Executive Officer and Treasurer
                         (principal executive officer and
                         principal accounting officer)

/s/ Roger C. Lucas       Vice Chairman and Director           October 19, 1995
Roger C. Lucas


/s/ Howard V. O'Connell  Director                             October 19, 1995
Howard V. O'Connell


/s/ G. Arthur Herbert    Director                             October 19, 1995
G. Arthur Herbert


/s/ Randolph C. Steer    Director                             October 19, 1995
Randolph C. Steer, M.D.


/s/ Lowell E. Sears      Director                             October 19, 1995
Lowell E. Sears