FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Kummeth Charles R.
  2. Issuer Name and Ticker or Trading Symbol
BIO-TECHNE Corp [TECH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
CHIEF EXECUTIVE OFFICER
(Last)
(First)
(Middle)
614 MCKINLEY PL N E
3. Date of Earliest Transaction (Month/Day/Year)
07/06/2022
(Street)

MINNEAPOLIS, MN 55413
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 07/06/2022   M   50,000 A $ 108.49 248,338 (1) D  
Common Stock 07/06/2022   F   30,935 D $ 362.78 217,403 (1) D  
Common Stock               100 I By Step-Son
Common Stock               100 I By Step-Daughter

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) $ 108.49 07/06/2022   M     50,000   (2) 08/07/2022 Common Stock 50,000 $ 0 45,346 D  
Stock Options (right to buy) $ 106.59               (2) 08/18/2023 Common Stock 256,010   256,010 D  
Stock Options (right to buy) $ 125.05               (2) 08/09/2024 Common Stock 194,771   194,771 D  
Stock Options (right to buy) $ 177.32               (2) 08/08/2025 Common Stock 90,334   90,334 D  
Stock Options (right to buy) $ 177.32               (3) 08/08/2025 Common Stock 60,222   60,222 D  
Restricted Stock Units (4)               (5)   (5) Common Stock 16,937   16,937 D  
Stock Options (right to buy) $ 190.41               (5) 08/07/2026 Common Stock 85,725   85,725 D  
Stock Options (right to buy) $ 190.41               (6) 08/07/2026 Common Stock 57,150   57,150 D  
Restricted Stock Units (4)               (7)   (7) Common Stock 12,879   12,879 D  
Stock Options (right to buy) $ 267.87               (7) 08/05/2027 Common Stock 57,442   57,442 D  
Stock Options (right to buy) $ 267.87               (8) 08/05/2027 Common Stock 38,295   38,295 D  
Stock Options (right to buy) $ 267.87               (9) 08/05/2027 Common Stock 16,650   16,650 D  
Stock Options (right to buy) $ 267.87               (10) 08/05/2027 Common Stock 16,650   16,650 D  
Restricted Stock Units (4)               (11)   (11) Common Stock 8,016   8,016 D  
Stock Options (right to buy) $ 481.82               (11) 08/06/2028 Common Stock 31,315   31,315 D  
Stock Options (right to buy) $ 481.82               (12) 08/06/2028 Common Sstock 20,876   20,876 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Kummeth Charles R.
614 MCKINLEY PL N E
MINNEAPOLIS, MN 55413
  X     CHIEF EXECUTIVE OFFICER  

Signatures

 /s/ Brenda S. Furlow, Attorney-in-Fact   06/09/2022
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes (i) 3,763 shares of restricted stock for which the risk of forfeiture will lapse on August 7, 2022; (ii) 5,724 shares of restricted stock for which the risk of forfeiture will lapse as to 2,862 shares on each of August 5, 2022 and August 5, 2023; and (iii) 5,344 shares of restricted stock for which the risk of forfeiture will lapse as to 1,782 shares on August 6, 2022 and as to 1,781 shares on each of August 6, 2023 and August 6, 2024.
(2) Fully exercisable.
(3) Options to purchase 15,056 shares vests on each of 8/8/2019 and 8/8/2020 and options to purchase 15,055 shares vests on each of 8/8/2021 and 8/8/2022.
(4) Each restricted stock unit represents a contingent right to receive one share of Bio-Techne common stock.
(5) Vests in full or in part on 8/7/2022 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(6) Options to purchase 14,288 shares vest on each of 8/7/2020 and 8/7/2021 and options to purchase 14,287 shares vest on each of 8/7/2022 and 6/7/2023.
(7) Vests in full or in part on 8/5/2023 if certain performance goals are achieved (or such later ate as performance is certified by the Administrator).
(8) Options to purchase 9,573 shares vest on 8/5/21 and options to purchase 9,574 shares vest on each of 8/5/22, 8/5/23 and 8/5/24.
(9) Vests in full on the date performance of certain product revenue goals during the period of fiscal 2021-2023 is certified by the Administrator, in no event earlier than 8/5/2021.
(10) Options to purchase 5,550 shares vest on each of 8/5/21, 8/5/22 and 8/5/23.
(11) Vests in full or in part on 8/6/2024 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(12) Options to purchase 5,219 shares vest on each of 8/6/2022, 8/6/2023, 8/6/2024 and 8/6/2025.

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